Abstract
Abstract
Adverse reactions to drugs can induce many different pattens of cutaneous inflammation. This chapter focuses on the non‐severe phenotypes including the exanthems, drug‐induced pruritus, eczema and systemic allergic contact dermatitis (including symmetrical drug‐related intertriginous and flexural exanthema, SDRIFE) as well as lichen planus and lichenoid reactions. Additionally, drug‐induced urticaria, angioedema and anaphylaxis are reviewed. Importantly, while evidence‐based lists of common drug causes for each presentation are considered, imputability alone is an unreliable means for clinicians to assess causality. Instead, an approach utilising drug ingestion timeline and careful clinical assessment of differential diagnosis is presented.