Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non‐cell‐autonomous neuronal damage

Author:

Matute‐Blanch Clara1ORCID,Brito Verónica234ORCID,Midaglia Luciana1ORCID,Villar Luisa M5ORCID,Garcia‐Diaz Barriga Gerardo2ORCID,Guzman de la Fuente Alerie6ORCID,Borrás Eva7,Fernández‐García Sara234ORCID,Calvo‐Barreiro Laura1ORCID,Miguez Andrés1ORCID,Costa‐Frossard Lucienne5ORCID,Pinteac Rucsanda1ORCID,Sabidó Eduard78ORCID,Alberch Jordi234ORCID,Fitzgerald Denise C.6ORCID,Montalban Xavier1ORCID,Comabella Manuel1ORCID

Affiliation:

1. Servei de Neurologia‐Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat). Institut de Recerca Vall d'Hebron (VHIR) Hospital Universitari Vall d'Hebron. Universitat Autònoma de Barcelona Barcelona Spain

2. Departament de Biomedicina, Facultat de Medicina Institut de Neurociències Universitat de Barcelona Barcelona Spain

3. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona Barcelona Spain

4. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) Madrid Spain

5. Departments of Neurology and Immunology Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigacion Sanitaria Madrid Spain

6. Wellcome‐Wolfson Institute for Experimental Medicine Queen's University Belfast, Belfast, UK

7. Proteomics Unit, Universitat Pompeu Fabra (UPF) Barcelona Spain

8. Proteomics Unit, Centre de Regulació Genòmica (CRG) Barcelona Institute of Science and Technology (BIST) Barcelona Spain

Funder

Wellcome Trust

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

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