Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study

Author:

Kim Bokyung1,Han Kyungdo2,Chung Hyunsoo1,Kim Sang Gyun1,Cho Soo‐Jeong1ORCID

Affiliation:

1. Department of Internal Medicine and Liver Research Institute Seoul National University Hospital Seoul National University College of Medicine Seoul Korea

2. Department of Statistics and Actuarial Science Soongsil University Seoul Korea

Abstract

AbstractBackgroundAlthough depression is associated with poor treatment outcomes in patients with cancer, little is known about whether lifestyle modifications could help prevent depression. The authors aimed to identify the effect of lifestyle modifications, including smoking cessation, alcohol abstinence, and starting regular physical activity, on new‐onset depression in patients with gastric cancer who underwent surgery.MethodsBy using the Korean National Health Insurance Service database, patients with gastric cancer who underwent surgery between 2010 and 2017 were identified. Self‐reported lifestyle behaviors within 2 years before and after surgery were analyzed using the health examination database. Patients were classified according to changes in lifestyle behaviors, and their risk of new‐onset depression was compared.ResultsAmong 18,902 patients, 2302 (12.19%) developed depression (26.00 per 1000 person‐years). Smoking cessation (hazard ratio [HR], 0.77; 95% confidence interval [CI], 0.66–0.91) and alcohol abstinence (HR, 0.79; 95% CI, 0.69–0.90) were associated with reduced risk of depression development compared with persistent smoking and persistent drinking, respectively. Starting regular physical activity was not associated with risk of depression. When lifestyle behaviors after gastrectomy were scored from 0 to 3 points (1 point each for not smoking, not drinking, and being physically active), the risk of depression tended to decrease as lifestyle scores increased from 0 points (reference) to 1 point (HR, 0.69; 95% CI, 0.55–0.83), 2 points (HR, 0.60; 95% CI, 0.50–0.76), and 3 points (HR, 0.55; 95% CI, 0.45–0.68).ConclusionsSmoking cessation and alcohol abstinence are associated with reduced risk of developing depression in patients with gastric cancer who undergo surgery.

Publisher

Wiley

Subject

Cancer Research,Oncology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3