Cardiogenic shock severity predicts bleeding events in patients with temporary mechanical circulatory support

Author:

Oyabu Kenjiro1,Hattori Hidetoshi1ORCID,Kikuchi Noriko1,Haruki Shintaro1,Minami Yuichiro1,Ichihara Yuki2,Saito Satoshi2,Nunoda Shinichi3,Niinami Hiroshi1,Yamaguchi Junichi1

Affiliation:

1. Department of Cardiology Tokyo Women's Medical University Tokyo Japan

2. Department of Cardiovascular Surgery Tokyo Women's Medical University Tokyo Japan

3. Department of Therapeutic Strategy for Severe Heart Failure Tokyo Women's Medical University Graduate School of Medicine Tokyo Japan

Abstract

AbstractBackgroundData on shock severity and bleeding events in patients with temporary mechanical circulatory support (tMCS) are limited. We investigated the relationship between the Society for Cardiovascular Angiography and Interventions (SCAI) shock stage classification and bleeding events in patients with tMCS.MethodsWe evaluated the data of 285 consecutive patients with tMCS who were admitted to our institution between June 2019 and May 2022. At the time of tMCS initiation, 81 patients (28.4%) were in SCAI stage A, 38 (13.3%) in stage B, 69 (24.2%) in stage C, 33 (11.6%) in stage D, and 64 (22.5%) in stage E. Multivariable logistic regression modeling was used to assess the association between the SCAI shock stage and in‐hospital bleeding events.ResultsIn‐hospital bleeding occurred in 100 patients (35.1%). The bleeding event rate increased incrementally across the SCAI shock stages (stage A, 11.1%; stage B, 15.8%; stage C, 37.7%; stage D, 54.6%; stage E, 64.1%). In‐hospital bleeding was associated with the SCAI shock stage (p < 0.001). Compared with stage A, the adjusted odds ratios for in‐hospital bleeding were 1.48 (95% confidence interval [CI] 0.47–4.66), 6.47 (95% CI 2.61–10.66), 11.59 (95% CI 3.77–35.64), and 7.85 (95% CI 2.51–24.55) for stages B, C, D, and E, respectively.ConclusionsThe SCAI shock stage predicted subsequent bleeding events in patients with tMCS. This simple scheme may be useful for tailored risk‐based clinical assessment and management of patients with tMCS.

Publisher

Wiley

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