Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization
Author:
Affiliation:
1. Department of Chemistry and BiochemistryThe Ohio State University 484 West 12th Avenue Columbus OH 43210 USA
2. Department of Molecular Virology, Immunology, and Medical GeneticsThe Ohio State University Columbus OH 43210 USA
Publisher
Wiley
Subject
General Chemistry,Catalysis
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201610888
Reference49 articles.
1. For excellent reviews on protein–protein interactions see:
2. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
3. Modulating protein–protein interactions: the potential of peptides
4. Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes
5. Strukturbasierte Entwicklung von Protein-Protein-Interaktionsinhibitoren: Stabilisierung und Nachahmung von Peptidliganden
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