Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants-Reference-Cited by-同舟云学术

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Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants

Published:2017-09-22 Issue:43 Volume:56 Page:13232-13236
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Bührmann Mike¹,Hardick Julia¹,Weisner Jörn¹,Quambusch Lena¹,Rauh Daniel¹^ORCID

Affiliation:

1. Faculty of Chemistry and Chemical Biology; TU Dortmund University; Otto-Hahn-Strasse 4a 44227 Dortmund Germany

Funder

German Federal Ministry for Education and Research (NGFNPlus and e:Med))

Deutsche Forschungsgemeinschaft (DFG)

North Rhine Westphalia (NRW) and the European Union (European Regional Development Fund: Investing In Your Future)

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201706345/fullpdf

Reference25 articles.

1. Kinase Drug Discovery – What’s Next in the Field?

2. Targeting cancer with small molecule kinase inhibitors

3. Protein kinases — the major drug targets of the twenty-first century?

4. Cell Commun. Signaling 2011 9 https://doi.org/10.1186/1478-811X-9-23

5. The Transcriptional Activator Mirk/Dyrk1B Is Sequestered by p38α/β MAP Kinase

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1. Solid-State Phosphine Ligand Engineering via Postsynthetic Modification of Amine-Functionalized Metal–Organic Frameworks;Organometallics;2024-01-31

2. Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation;Science;2023-09-15

3. Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation;2022-07-04

4. Targeting the non‐ATP‐binding pocket of the MAP kinase p38γ mediates a novel mechanism of cytotoxicity in cutaneous T‐cell lymphoma (CTCL);FEBS Letters;2021-09-15

5. Binding mechanism of inhibitors to p38α MAP kinase deciphered by using multiple replica Gaussian accelerated molecular dynamics and calculations of binding free energies;Computers in Biology and Medicine;2021-07

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