Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H 3 R Antagonism for Neurodegenerative Diseases-Reference-Cited by-同舟云学术

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H 3 R Antagonism for Neurodegenerative Diseases

Published:2017-09 Issue:41 Volume:56 Page:12765-12769
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Bautista‐Aguilera Óscar M.¹^ORCID,Hagenow Stefanie²^ORCID,Palomino‐Antolin Alejandra³^ORCID,Farré‐Alins Víctor³^ORCID,Ismaili Lhassane⁴^ORCID,Joffrin Pierre‐Louis⁵,Jimeno María L.¹^ORCID,Soukup Ondřej⁶^ORCID,Janočková Jana⁶,Kalinowsky Lena⁷^ORCID,Proschak Ewgenij⁷,Iriepa Isabel⁸,Moraleda Ignacio⁸^ORCID,Schwed Johannes S.²,Romero Martínez Alejandro⁹^ORCID,López‐Muñoz Francisco¹⁰,Chioua Mourad¹,Egea Javier³^ORCID,Ramsay Rona R.⁵^ORCID,Marco‐Contelles José¹,Stark Holger²^ORCID

Affiliation:

1. Laboratorio de Química Médica Instituto de Química Orgánica General CSIC and Centro de Química Orgánica “Lora-Tamayo”, CSIC C/ Juan de la Cierva 3 28006 Madrid Spain

2. Institut für Pharmazeutische und Medizinische Chemie Heinrich-Heine-Universität Düsseldorf Universitätsstrasse 1 40225 Düsseldorf Germany

3. Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica Hospital Universitario de la Princesa Calle de Diego de León, 62 28006 Madrid Spain

4. Neurosciences Intégratives et Cliniques EA 481 Université Bourgogne Franche-Comté Rue Ambroise Paré 25000 Besançon France

5. Biomedical Sciences Research Complex University of St Andrews, Biomolecular Sciences Building North Haugh St Andrews KY16 9ST UK

6. Centrum biomedicínského výzkumu Fakultní nemocnice Hradec Králové Sokolska 581 50005 Hradec Kralove Czech Republic

7. Institut für Pharmazeutische Chemie Goethe Universität Frankfurt Max-von-Laue-Strasse 9 60438 Frankfurt Germany

8. Departamento de Química Orgánica y Química Inorgánica Universidad de Alcalá Ctra. Madrid-Barcelona, Km. 33,6 28871 Madrid Spain

9. Departamento de Toxicología y Farmacología Facultad de Veterinaria, UCM Av. Puerta de Hierro, s/n 28040 Madrid Spain

10. Universidad Camilo José Cela C/ Castillo de Alarcón, 49 28692 Villanueva de la Cañada Madrid Spain

Funder

Ministerio de Economía y Competitividad

Universidad Camilo José Cela

Fondo de Investigaciones Sanitarias

MHCZ-DRO

European Cooperation in Science and Technology

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201706072

Reference31 articles.

1. The Role of Oxidative Stress in Neurodegenerative Diseases

2. Oxidative Stress in Neurodegenerative Diseases

3. N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor

4. Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

5. Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

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