1. Center of Marine Biotechnology and Biomedicine; Scripps Institution of Oceanography; University of California at San Diego; 9500 Gilman Drive La Jolla CA 92093-0204 USA
2. Graduate School of Pharmaceutical Sciences; The University of Tokyo; 7-3-1 Hongo, Bunkyo-ku Tokyo 113-0033 Japan
3. Skaggs School of Pharmacy and Pharmaceutical Sciences; University of California at San Diego; 9500 Gilman Drive La Jolla CA 92093 USA