Discovery of substituted indole derivatives as allosteric inhibitors ofm6A‐RNAmethyltransferase,METTL3‐14 complex
Author:
Affiliation:
1. School of Life Sciences Gwangju Institute of Science and Technology (GIST) Gwangju Republic of Korea
2. Center for AI‐Applied High Efficiency Drug Discovery (AHEDD) Gwangju Institute of Science and Technology (GIST) Gwangju Republic of Korea
Funder
Korea Research Institute of Chemical Technology
Publisher
Wiley
Subject
Drug Discovery
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21910
Reference30 articles.
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3. A mass spectrometric assay of METTL3/METTL14 methyltransferase activity;Buker S. M.;SLAS DISCOVERY: Advancing the Science of Drug Discovery,2020
4. Reactions of functionalized sulfonamides: Application to lowering the lipophilicity of cytosolic phospholipase A2α inhibitors;Chen L.;Journal of Medicinal Chemistry,2009
5. The role of M6A RNA methylation in human cancer;Chen X.‐Y.;Molecular Cancer,2019
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