BCR/ABLlevel at 6 months identifies good risk CML subgroup after failing early molecular response at 3 months following imatinib therapy for CML in chronic phase

Author:

Kim Dennis Dong Hwan1,Hamad Nada1,Lee Hong Gi1,Kamel-Reid Suzanne2,Lipton Jeffrey H.1

Affiliation:

1. Department of Medical Oncology and Hematology; Princess Margaret Hospital, University Health Network, University of Toronto; Ontario Canada

2. Department of Pathology; Toronto General Hospital, University Health Network, University of Toronto; Ontario Canada

Publisher

Wiley

Subject

Hematology

Reference14 articles.

1. Assessment of BCR-ABL1 Transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors;Marin;J Clin Oncol,2012

2. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML);Hanfstein;Leukemia,2012

3. Dasatinib and imatinib-induced reductions in BCR-ABL transcript levels below 10% at 3 months are associated with improved responses in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): Analysis of molecular response kinetics in the DASISION trial;Hochhaus;Blood (ASH Annual Meeting Abstracts),2011

4. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML);Hanfstein;Leukemia,2012

5. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013;Baccarani;Blood,2013

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