Automated radiochemical synthesis of pharmaceutical grade [ <sup>18</sup> F]FLT using 3‐N‐Boc‐5′‐O‐dimethoxytrityl‐3′‐O‐nosyl‐thymidine precursor and its Sep‐Pak® purification employing selective elution from reversed phase-Reference-Cited by-同舟云学术

Automated radiochemical synthesis of pharmaceutical grade [ ¹⁸ F]FLT using 3‐N‐Boc‐5′‐O‐dimethoxytrityl‐3′‐O‐nosyl‐thymidine precursor and its Sep‐Pak® purification employing selective elution from reversed phase

Published:2022-05-16 Issue:8 Volume:65 Page:206-222
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:Labelled Comp Radiopharmac

Author:

Mitra Arpit¹,Chakraborty Avik²³,Upadhye Trupti²,Tawate Megha²,Lad Sangita²,Sahu Sudeep²,Rajesh Chinagandham²,Bagul Swati²,Pawar Yogita²,Ray Mukti Kant²³,Banerjee Sharmila³⁴^ORCID

Affiliation:

1. Radiopharmaceuticals Laboratory Board of Radiation and Isotope Technology Navi Mumbai India

2. Radiation Medicine Centre Bhabha Atomic Research Centre Mumbai India

3. Department of Chemical Sciences and Life Sciences Homi Bhabha National Institute Mumbai India

4. Advanced Centre for Treatment, Research and Education in Cancer Tata Memorial Centre Navi Mumbai India

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jlcr.3974

Reference29 articles.

1. WalshJ PadgettH.Method for preparing radiolabeled thymidine.2003.https://patents.google.com/patent/US20050131224A1/en?oq=US+2005%2F0131224A1

2. Radiosynthesis of 3′-Deoxy-3′-[18F]Fluorothymidine ([18F]FLT)

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