An insight into the thermodynamic characteristics of human thrombopoietin complexation with TN1 antibody

Author:

Arai Shigeki1,Shibazaki Chie1,Adachi Motoyasu1,Honjo Eijiro1,Tamada Taro1,Maeda Yoshitake2,Tahara Tomoyuki2,Kato Takashi3,Miyazaki Hiroshi4,Blaber Michael5,Kuroki Ryota1

Affiliation:

1. Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, 2-4 Shirakata; Tokai Ibaraki 319-1106 Japan

2. Kyowa Hakko Kirin Co. Ltd; 3-6-6 Asahi-Cho Machida Tokyo 194-8533 Japan

3. Department of Biology, Faculty of Education and Integrated Arts and Sciences; Waseda University; 2-2 Wakamatsu, Shinjuku Tokyo 162-8480 Japan

4. Department of Innovative Drug Discovery and Development; Japan Agency for Medical Research and Development; 1-5-5 Nihonbashi-muromachi, Chuo Tokyo 103-0022 Japan

5. College of Medicine; Florida State University; 1115 West Call Street, Tallahassee Florida 32306-4300, USA

Funder

Protein 3000 Project

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference67 articles.

1. Thrombopoietin: its role from early hematopoiesis to platelet production;Wendling;Haematologica,1999

2. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl;Bartley;Cell,1994

3. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand;Sauvage;Nature,1994

4. Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates;Farese;Blood,1995

5. The glycan domain of thrombopoietin enhances its secretion;Linden;Biochemistry,2000

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