Main chemical constituents and mechanism of anti‐tumor action of Solanum nigrum L

Author:

Zhao Zhen‐duo1,Hu Cheng2ORCID,Li Ling3,Zhang Jia‐qi1ORCID,Zhang Li‐chao1

Affiliation:

1. Department of Pharmacy, Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Shanghai China

2. Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine Shanghai China

3. Institute of Vascular Anomalies, Shanghai TCM‐Integrated Hospital, Shanghai University of Traditional Chinese Medicine Shanghai China

Abstract

AbstractObjectiveSolanum nigrum L. (SNL) is a natural drugwith diverse bioactive components and multi‐targeted anti‐tumor effects, gaining increasing attention in clinical application.Method and ResultsThis paper reviews the studies on SNL by searching academic databases (Google Scholar, PubMed, Science Direct,and Web of Science, among others), analyzing its chemical compositions (alkaloids, saponins, polysaccharides, and polyphenols, among others), andbriefly describes the anti‐tumor mechanisms of the main components.DiscussionThis paper discusses the shortcomings of the current research on SNL and proposes corresponding solutions, providing theoretical support for further research on its biological functions and clinical efficacy.

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

Wiley

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