Higher preoperative serum levels of PD ‐L1 and B7‐H4 are associated with invasive and metastatic potential and predictable for poor response to VEGF ‐targeted therapy and unfavorable prognosis of renal cell carcinoma

Author:

Fukuda Takehiko1,Kamai Takao1,Masuda Akinori2,Nukui Akinori3,Abe Hideyuki1,Arai Kyoko1,Yoshida Ken‐Ichiro1

Affiliation:

1. Department of Urology Dokkyo Medical University Tochigi Japan

2. Dialysis center Dokkyo Medical University Koshigaya Hospital Saitama Japan

3. Department of Urology Nasu Red Cross Hospital Tochigi Japan

Funder

Japanese Science Progress Society KAKENHI

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference35 articles.

1. Cancer statistics, 2012

2. Renal cell carcinoma

3. The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer

4. Proliferative activity of intratumoral CD8(+) T‐lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity;Nakano O.;Cancer Res.,2001

5. Human renal carcinoma antigen‐specific CTLs, antigen‐driven selection and long‐term persistence in vivo;Jantzer P.;Cancer Res.,1998

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