Affiliation:
1. College of Chemistry Zhengzhou University Zhengzhou Henan 450001 China
2. Department of Chemistry Zhejiang University Hangzhou Zhejiang 310058 China
Abstract
Comprehensive SummaryA mechanistically distinctive visible‐light‐promoted metal‐free aerobic oxidation of alkenyl silanes with alcohols was disclosed to efficiently construct α‐alkoxy ketones under mild conditions. The primary, secondary, and tertiary alcohols could be used as reactants. The protocol could be carried out on a gram‐scale. Various derivatizations of products could be conducted. Mechanistic studies indicated the reaction was initiated by single‐electron oxidation of the alkenyl silanes, rather than radical addition to alkenyl silanes.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
National Key Research and Development Program of China