AggScore: Prediction of aggregation-prone regions in proteins based on the distribution of surface patches-Reference-Cited by-同舟云学术

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AggScore: Prediction of aggregation-prone regions in proteins based on the distribution of surface patches

Published:2018-09-27 Issue:11 Volume:86 Page:1147-1156
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Sankar Kannan¹^ORCID,Krystek Stanley R.²,Carl Stephen M.³,Day Tyler¹,Maier Johannes K. X.¹

Affiliation:

1. Schrödinger Inc.; New York New York

2. Molecular Discovery Technologies, Bristol-Myers Squibb; Princeton New Jersey

3. Discovery Pharmaceutics and Analytical Sciences and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb; Princeton New Jersey

Funder

Schrodinger, Inc.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.25594/fullpdf

Reference57 articles.

1. Recent advances in (therapeutic protein) drug development;Lagassé;F1000Research,2017

2. Protein aggregation and bioprocessing;Cromwell;AAPS J.,2006

3. When good goes awry: the aggregation of protein therapeutics;Redington;Protein Pept Lett.,2017

4. Protein aggregation diseases: pathogenicity and therapeutic perspectives;Aguzzi;Nat Rev Drug Discov.,2010

5. Lowe D Dudgeon K Rouet R Schofield P Jermutus L Christ D. 2011 84 41 61

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