Affiliation:
1. Department of Chemistry, Faculty of Science and Arts Najran University Najran Saudi Arabia
2. Department of Chemistry College of Science Qassim University Buraidah 51452 Saudi Arabia
3. Department of Chemistry, Faculty of Science Cairo University Giza 12613 Egypt
Abstract
AbstractThe microbial resistance to the traditional antibiotics causes serious health problems and increases day by day. Thus, there is a pressing need to discover alternative antimicrobial agents of different nature than that of the conventional antibiotics. For this, novel hydrogel nanocomposite films are prepared by chemical crosslinking grafting of carboxymethyl cellulose with N,N′‐methylene‐bis‐acrylamide (CMC‐g‐MBA), which subsequently followed by loading two different weight ratios of titanium oxide nanoparticles (TiO2NPs), such as 3% (CMC‐g‐MBA/TiO2NPs‐3%) and 5% (CMC‐g‐MBA/TiO2NPs‐5%) wt%. Their chemical structure and surface morphology are confirmed using appropriate analytical techniques. Their antimicrobial activity can be arranged as follows: CMC‐g‐MBA/TiO2NPs‐5% composite > CMC‐g‐MBA/TiO2NPs‐3% composite > CMC‐g‐MBA hydrogel. While, the native CMC has no observable antimicrobial effect. CMC‐g‐MBA/TiO2NPs‐3% composite imparts good barrier properties to the coated tomato fruits, delaying their spoilage and protecting them from the environmental microbes compared to the uncoated ones. CMC‐g‐MBA/TiO2NPs‐5% composite is safe on the normal human cells. Thus, incorporation of both MBA and TiO2NPs into CMC greatly develops its antimicrobial activity and provides a wonderful approach to attain promising materials that can efficiently compete with conventional antibiotics.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献