A lymphodepleted non‐human primate model for the assessment of acute on‐target and off‐tumor toxicity of human chimeric antigen receptor‐T cells-Reference-Cited by-同舟云学术

A lymphodepleted non‐human primate model for the assessment of acute on‐target and off‐tumor toxicity of human chimeric antigen receptor‐T cells

Published:2021-01 Issue:6 Volume:10 Page:
ISSN:2050-0068
Container-title:Clinical & Translational Immunology
language:en
Short-container-title:Clin Transl Immunol

Author:

Yagyu Shigeki¹²^ORCID,Mochizuki Hidemi²³,Yamashima Kumiko¹⁴,Kubo Hiroshi¹,Saito Shoji²⁵^ORCID,Tanaka Miyuki²⁵^ORCID,Sakamoto Kengo³,Shimoi Akihito²³,Nakazawa Yozo²⁵⁶^ORCID

Affiliation:

1. Department of Pediatrics Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan

2. Center for Advanced Research of Gene and Cell Therapy in Shinshu University (CARS) Shinshu University School of Medicine Matsumoto Japan

3. Ina Research Inc. Ina Japan

4. Division of Cancer Immunotherapy Exploratory Oncology Research and Clinical Trial Center National Cancer Center Kashiwa Japan

5. Department of Pediatrics Shinshu University School of Medicine Matsumoto Japan

6. Institute for Biomedical Sciences Interdisciplinary Cluster for Cutting Edge Research Shinshu University Matsumoto Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science London

Publisher

Wiley

Subject

General Nursing,Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cti2.1291

Reference26 articles.

1. Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

2. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

3. Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells

4. Safety of Targeting ROR1 in Primates with Chimeric Antigen Receptor–Modified T Cells

5. Autologous non‐human primate model for safety assessment of piggyBac transposon‐mediated chimeric antigen receptor T cells on granulocyte–macrophage colony‐stimulating factor receptor

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