Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART-Reference-Cited by-同舟云学术

Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART

Published:2022-08-09 Issue:4 Volume:92 Page:532-544
ISSN:0364-5134
Container-title:Annals of Neurology
language:en
Short-container-title:Annals of Neurology

Author:

Cochrane Catherine R.¹²^ORCID,Angelovich Thomas A.¹³⁴^ORCID,Byrnes Sarah J.¹,Waring Emily¹²,Guanizo Aleks C.¹,Trollope Gemma S.¹²,Zhou Jingling¹,Vue Judith¹,Senior Lachlan¹,Wanicek Emma¹,Eddine Janna Jamal¹,Gartner Matthew J.⁴^ORCID,Jenkins Trisha A.¹^ORCID,Gorry Paul R.¹⁵⁶^ORCID,Brew Bruce J.⁷^ORCID,Lewin Sharon R.⁴⁵⁸^ORCID,Estes Jacob D.⁹^ORCID,Roche Michael¹⁴^ORCID,Churchill Melissa J.¹³¹⁰^ORCID

Affiliation:

1. Emerging Infections Program, School of Health and Biomedical Sciences RMIT University Melbourne VIC Australia

2. Department of Medicine The Royal Melbourne Hospital, The University of Melbourne Melbourne VIC Australia

3. Life Sciences Burnet Institute Melbourne VIC Australia

4. Department of Infectious Diseases The University of Melbourne at the Peter Doherty Institute for Infection and Immunity Melbourne VIC Australia

5. Department of Infectious Diseases Alfred Hospital and Monash University Melbourne VIC Australia

6. Department of Microbiology and Immunology The University of Melbourne at the Peter Doherty Institute for Infection and Immunity Melbourne VIC Australia

7. Peter Duncan Neurosciences Unit, Departments of Neurology and Immunology St Vincent's Hospital Sydney, University of New South Wales and University of Notre Dame Sydney New South Wales Australia

8. Victorian Infectious Diseases Service Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity Melbourne VIC Australia

9. Vaccine and Gene Therapy Institute, Oregon National Primate Research Centre Oregon Health & Science University Portland OR USA

10. Departments of Microbiology and Medicine Monash University Melbourne VIC Australia

Funder

National Health and Medical Research Council

National Institute on Drug Abuse

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ana.26456

Reference46 articles.

1. Defining total-body AIDS-virus burden with implications for curative strategies

2. Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

3. Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues

4. Macrophages but not Astrocytes Harbor HIV DNA in the Brains of HIV-1-Infected Aviremic Individuals on Suppressive Antiretroviral Therapy

5. Brain Cell Reservoirs of Latent Virus in Presymptomatic HIV-Infected Individuals

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