Phase 2 trial with imeglimin in patients with Type 2 diabetes indicates effects on insulin secretion and sensitivity
Author:
Affiliation:
1. Poxel SA Lyon France
2. University of Latvia Riga Latvia
3. Institute of Neuroscience National Research Council Padova Italy
4. Independent Researcher Padova Italy
Funder
National Research Council Sri Lanka
Publisher
Wiley
Subject
Endocrinology, Diabetes and Metabolism
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/edm2.371
Reference41 articles.
1. Pathophysiology of Type 2 Diabetes Mellitus
2. The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes
3. Role of mitochondria in pathogenesis of type 2 diabetes mellitus
4. Targeting Mitochondria in Diabetes
5. Reduced lactic acidosis risk with Imeglimin: Comparison with Metformin
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2. Exploring new mechanisms of Imeglimin in diabetes treatment: Amelioration of mitochondrial dysfunction;Biomedicine & Pharmacotherapy;2024-06
3. Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic β-cells from db/db mice;Scientific Reports;2024-03-14
4. Curcuma longa extract reduces serum inflammatory markers and postprandial hyperglycemia in healthy but borderline participants with overweight and glycemia in the normal/prediabetes range: a randomized, double-blind, and placebo-controlled trial;Frontiers in Nutrition;2024-01-29
5. Different doses of imeglimin for management of type 2 diabetes mellitus: a systematic review, meta-analysis, and meta-regression of randomized clinical trials;Expert Review of Endocrinology & Metabolism;2023-12-04
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