Comparative analysis of absorbed ingredients and metabolites, and pharmacokinetic studies of Zhimu–Huangbai herb pair in the plasma of normal and type 2 diabetes mellitus rats by UHPLC‐linear trap quadrupole‐orbitrap MS and LC‐MS/MS-Reference-Cited by-同舟云学术

Comparative analysis of absorbed ingredients and metabolites, and pharmacokinetic studies of Zhimu–Huangbai herb pair in the plasma of normal and type 2 diabetes mellitus rats by UHPLC‐linear trap quadrupole‐orbitrap MS and LC‐MS/MS

Published:2021-12-03 Issue:3 Volume:45 Page:664-676
ISSN:1615-9306
Container-title:Journal of Separation Science
language:en
Short-container-title:J of Separation Science

Author:

Cao Yingying¹^ORCID,Sun Zhengang²,Huang Hailan¹,Lin Aihua¹,Liu Yiming¹³

Affiliation:

1. The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine Guangzhou P. R. China

2. Department of Pharmacy, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology Xiaogan P. R. China

3. Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome Guangzhou P. R. China

Funder

Science and Technology Planning Project of Guangdong Province

Traditional Chinese Medicine Bureau of Guangdong Province

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jssc.202100582

Reference34 articles.

1. Application of GC/MS-based metabonomic profiling in studying the therapeutic effects of Huangbai–Zhimu herb-pair (HZ) extract on streptozotocin-induced type 2 diabetes in mice

2. Reversal of Muscle Atrophy by Zhimu-Huangbai Herb-Pair via Akt/mTOR/FoxO3 Signal Pathway in Streptozotocin-Induced Diabetic Mice

3. Effects and mechanism of anemarrhenae rhizoma‐phellodendri chinensis cortex medicine effective parts to improve cognitive impairment in type 2 diabetic rats;Liu J;Chin. Tradit. Herb. Drugs,2017

4. RP-HPLC determination and pharmacokinetic study of mangiferin in rat plasma after taking traditional chinese medicinal-preparation: Zhimu decoction

5. Analysis of berberine and total alkaloid content in Cortex Phellodendri by near infrared spectroscopy (NIRS) compared with high-performance liquid chromatography coupled with ultra-visible spectrometric detection

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