Optimizing cationic and neutral lipids for efficient gene delivery at high serum content

Author:

Chan Chia-Ling12,Ewert Kai K.1ORCID,Majzoub Ramsey N.1,Hwu Yeu-Kuang2,Liang Keng S.34,Leal Cecília15,Safinya Cyrus R.1

Affiliation:

1. Department of Materials, Department of Physics and Molecular, Cellular & Developmental Biology Department; University of California at Santa Barbara; CA USA

2. Institute of Physics; Academia Sinica; Taipei Taiwan

3. National Synchrotron Radiation Research Center; Hsinchu Taiwan

4. Department of Electrophysics; National Chiao-Tung University; Hsinchu Taiwan

5. Department of Materials Science and Engineering; University of Illinois; Urbana IL USA

Publisher

Wiley

Subject

Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference68 articles.

1. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure;Felgner;Proc Natl Acad Sci U S A,1987

2. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations;Felgner;J Biol Chem,1994

3. Nonviral gene delivery: what we know and what is next;Gao;AAPS J,2007

4. In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes;Fortunati;Biochim Biophys Acta,1996

5. Time-dependent maturation of cationic liposome-DNA complex for serum resistance;Yang;Gene Ther,1998

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