Early intervention and care for Diabetic Foot Ulcers in Low and Middle Income Countries: Addressing challenges and exploring future strategies: A narrative review

Author:

Swaminathan Niranjna1,Awuah Wireko Andrew2,Bharadwaj Hareesha Rishab3,Roy Sakshi4,Ferreira Tomas5ORCID,Adebusoye Favour Tope2ORCID,Ismail Isma Farah Nurlisa binti1,Azeem Saleha6ORCID,Abdul‐Rahman Toufik2ORCID,Papadakis Marios7

Affiliation:

1. School of Medicine Taylor's University Selangor Malaysia

2. Faculty of Medicine Sumy State University Sumy Ukraine

3. Faculty of Biology Medicine and Health The University of Manchester Manchester UK

4. School of Medicine Queen's University Belfast Belfast UK

5. School of Clinical Medicine University of Cambridge Cambridge UK

6. Faculty of Medicine King Edward Medical University Lahore Pakistan

7. Department of Surgery II, University Hospital Witten‐Herdecke, Heusnerstrasse 40 University of Witten‐Herdecke Wuppertal Germany

Abstract

AbstractBackground and AimsDiabetic Foot Ulcers (DFUs) are a significant health concern, particularly in Low‐ and Middle‐Income Countries (LMICs). This review explores key strategies for managing DFUs in LMICs, including integrating podiatry, endocrinology, and wound care services, educating patients, promoting self‐care, and preventive measures to reduce amputation rates.MethodsA comprehensive literature review was conducted, focusing on studies conducted in Low and Middle Income Countries to facilitate a qualitative analysis. The review examined the aetiology and risk factors to developing DFUs, clinical presentation, multidisciplinary management and evidence based interventions, challenges to the provision of care and future directions, all pertaining to DFUs in low and middle income countries.ResultsThe aetiology and risk factors contributing to the development of DFUs are complex and multifaceted. Factors such as limited access to health care, inadequate diabetes management, and socioeconomic disparities significantly influence the incidence of DFUs. Clinical presentation varies, with patients often presenting at advanced stages of the disease due to delayed or missed diagnoses. Multidisciplinary management, incorporating podiatry, endocrinology, and wound care services, has exhibited substantial promise in enhancing patient outcomes. Evidence‐based interventions, including offloading techniques, wound debridement, and the use of advanced wound dressings, have proven effective in promoting ulcer healing.ConclusionThe burden of DFUs in LMICs requires comprehensive strategies. Integrating podiatry, endocrinology, and wound care services, along with patient education and self‐care practices, is essential for reducing amputations and improving patients' quality of life. Regular follow‐up and early detection are vital for effective DFU management, emphasizing the need for ongoing research and investment in LMIC health care infrastructure. Embracing these multidisciplinary, patient‐centered approaches can effectively address the challenge of DFUs in LMICs, leading to better patient outcomes and improved quality of life.

Publisher

Wiley

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