Discovery of octahydropyrrolo [3,2‐b] pyridin derivative as a highly selective Type I inhibitor of FGFR3 over VEGFR2 by high‐throughput virtual screening
Author:
Affiliation:
1. Department of Chemistry Shantou University Shantou China
2. Medical Informatics Research Center Shantou University Medical College Shantou China
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.30357
Reference67 articles.
1. Targeting FGFR pathway in breast cancer
2. Roles of Fibroblast Growth Factor Receptors in Carcinogenesis
3. Fibroblast growth factor signalling: from development to cancer
4. Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2
5. In search of novel inhibitors of anti-cancer drug target fibroblast growth factor receptors: Insights from virtual screening, molecular docking, and molecular dynamics
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