Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d -Transpeptidases and Serine β-Lactamase Cysteine Variants
Author:
Affiliation:
1. Department of Chemistry; University of Oxford; Oxford OX1 3TA UK
2. School of Cellular and Molecular Medicine; University of Bristol; Bristol BS8 1TD UK
Funder
Tres Cantos Open Lab Foundation
Biotechnology and Biological Sciences Research Council
Medical Research Council
Wellcome Trust
Publisher
Wiley
Subject
General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ange.201809424/fullpdf
Reference34 articles.
1. An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway
2. Targeting a cell wall biosynthesis hot spot
3. Bacterial cell wall assembly: still an attractive antibacterial target
4. Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance
5. The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by l,d -Transpeptidation
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1. Selective Synthesis of Non‐Aromatic Five‐Membered Sulfur Heterocycles from Alkynes by using a Proton Acid/ N ‐Chlorophthalimide System;Angewandte Chemie International Edition;2020-11-18
2. Selective Synthesis of Non‐Aromatic Five‐Membered Sulfur Heterocycles from Alkynes by using a Proton Acid/ N ‐Chlorophthalimide System;Angewandte Chemie;2020-11-18
3. A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase Ldt Mt2;ChemBioChem;2019-11-08
4. Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2 with cysteine-reactive inhibitors including ebselen;Chemical Communications;2019
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