Intestinal secretion of indoxyl sulfate as a possible compensatory excretion pathway in chronic kidney disease

Author:

Morimoto Kaori1ORCID,Tominaga Yuuta1,Agatsuma Yuta1,Miyamoto Masanari1,Kashiwagura Shota1,Takahashi Akira1,Sano Yoshimi1,Yano Kentaro2,Kakinuma Chihaya2,Ogihara Takuo2,Tomita Mikio1

Affiliation:

1. Faculty of Pharmacy; Tohoku Medical and Pharmaceutical University; Sendai Japan

2. Faculty of Pharmacy; Takasaki University of Health and Welfare; Takasaki Japan

Funder

Grants-in-Aid for Scientific Research KAKENHI

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference18 articles.

1. OST alpha-OST beta a key membrane transporter of bile acids and conjugated steroids;Ballatori;The Content of the Frontiers in Bioscience (Landmark Ed),2009

2. Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients;Barreto;Clinical Journal of the American Society of Nephrology,2009

3. Pharmacokinetics and tissue distribution of uraemic indoxyl sulphate in rats;Deguchi;Biopharmaceutics & Drug Disposition,2003

4. The effect of albumin on MRP2 and BCRP in the vesicular transport assay;Deng;PLoS One,2016

5. Normal and pathologic concentrations of uremic toxins;Duranton;Journal of the American Society of Nephrology,2012

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