Therapeutic potential of hypnotic herbal medicines: A comprehensive review

Author:

Ghasemzadeh Rahbardar Mahboobeh1ORCID,Hosseinzadeh Hossein12ORCID

Affiliation:

1. Pharmaceutical Research Center Pharmaceutical Technology Institute, Mashhad University of Medical Sciences Mashhad Iran

2. Department of Pharmacodynamics and Toxicology School of Pharmacy, Mashhad University of Medical Sciences Mashhad Iran

Abstract

AbstractInsomnia affects millions of people worldwide, prompting considerable interest in herbal remedies for its treatment. This review aims to assess the therapeutic potential of such remedies for insomnia by analyzing current scientific evidence. The analysis identified several herbs, including Rosmarinus officinalis, Crocus sativus, Rosa damascena, Curcuma longa, Valeriana officinalis, Lactuca sativa, Portulaca oleracea, Citrus aurantium, Lippia citriodora, and Melissa officinalis, which show promise in improving overall sleep time, reducing sleep latency, and enhancing sleep quality. These plants act on the central nervous system, particularly the serotonergic and gamma‐aminobutyric acid (GABA)ergic systems, promoting sedation and relaxation. However, further research is necessary to fully understand their mechanisms of action, optimal dosages, and treatment protocols. Combining herbal medicines with conventional treatments may offer an effective natural alternative for those seeking medication. Nevertheless, individuals should consult their healthcare provider before using herbal remedies for insomnia. While this review provides evidence supporting their use, additional high‐quality studies are needed to firmly establish their clinical efficacy.

Publisher

Wiley

Reference158 articles.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Toxicity and safety of rosemary (Rosmarinus officinalis): a comprehensive review;Naunyn-Schmiedeberg's Archives of Pharmacology;2024-08-03

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