Real‐Time Detection of Sub‐ppm Aromatic Compounds in Alcohol by Surface Plasmon Resonance Using Label‐Free Graphene

Author:

Cho Sung Hwan1,Suh Jun Min12,Kim Wontaek3,Kim Jaehyun1,Kim Yeong Jae1,Lee Tae Hyung1,Kim Jae Young1,Sim Jaegun4,Choi Seung Won1,Hong Byung Hee4,Kim So Young3,Jang Ho Won1ORCID

Affiliation:

1. Department of Materials Science and Engineering, Research Institute of Advanced Materials Seoul National University Seoul 08826 Korea

2. Department of Mechanical Engineering Massachusetts Institute of Technology Cambridge MA 02139 USA

3. Infra Analysis Team, Global Manufacturing & Infra Technology Samsung Electronics Hwaseong 18448 Korea

4. Department of Chemistry Seoul National University Seoul 08826 Korea

Abstract

The increasing importance of high‐purity isopropyl alcohol (IPA) in semiconductor processing technology has led to a higher demand for technologies capable of detecting impurities in IPA. Although accurate and various impurity detection technologies have been developed, most of them have limitations in real‐time and repeatable detection of impurities. Herein, for the first time, surface plasmon resonance (SPR) sensor was developed utilizing graphene transferred Au film (Au/graphene) to detect sub‐ppm levels of 2,4‐dinitrophenol (2,4‐DNP) dissolved in IPA and this sensor demonstrates the ability to detect 2,4‐DNP in real‐time with great reversibility. The adsorption of 2,4‐DNP to graphene is found to be stronger than that for Au film because of noncovalent graphene π–π stacking interaction, and the effect of graphene is demonstrated through density function theory (DFT) calculations and enhancement in sensing performance of Au/graphene sensor. Additionally, the presence of noncovalent π–π stacking interaction between 2,4‐DNP and graphene has been demonstrated by confirming the p‐doping effect of graphene‐based solution field‐effect transistor measurements and consecutive Raman spectra analysis. This study offers experimental and theoretical insights into the adsorption kinetics of 2,4‐DNP dissolved in IPA and provides promising perspectives for real‐time sensing technology utilizing label‐free graphene to detect impurities in high‐purity cleaning agents.

Publisher

Wiley

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