Bioreactor scale up and protein product quality characterization of piggyBac transposon derived CHO pools

Author:

Rajendra Yashas1ORCID,Balasubramanian Sowmya2,Peery Robert B.1,Swartling James R.2,McCracken Neil A.2,Norris Dawn L.2,Frye Christopher C.2,Barnard Gavin C.1

Affiliation:

1. Biotechnology Discovery Research; Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center; Indianapolis IN 46225

2. Bioprocess Research and Development; Eli Lilly and Company, LTC-North; 1200 Kentucky Avenue Indianapolis IN 46221

Publisher

Wiley

Subject

Biotechnology

Reference17 articles.

1. The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line;Xu;Nat Biotechnol.,2011

2. Recombinant protein therapeutics from CHO cells-20 years and counting;Jayapal;Chem Eng Prog,2007

3. CHO cells in biotechnology for production of recombinant proteins: Current state and further potential;Kim;Appl Microbiol Biotechnol.,2011

4. Human cell lines for biopharmaceutical manufacturing: History, status, and future perspectives;Dumont;Crit Rev Biotechnol.,2015

5. Biopharmaceutical benchmarks 2014;Walsh;Nat Biotechnol.,2014

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