Orthognathic surgery in a patient with osteogenesis imperfecta and low von Willebrand factor

Author:

Himejima Akio12ORCID,Ueno Shuji2,Yamada Koji2,Kamitani Masayuki2,Hosoyama Chikako3,Iseki Tomio1

Affiliation:

1. First Department of Oral and Maxillofacial Surgery Osaka Dental University Osaka Japan

2. Department of Oral and Maxillofacial Surgery Kishiwada City Hospital Osaka Japan

3. Department of Orthodontics Osaka Dental University Osaka Japan

Abstract

AbstractBackgroundThis report describes the case of a patient with jaw deformity, osteogenesis imperfecta (OI), and low von Willebrand factor (low VWF).Case presentationA 30‐year‐old woman with OI was referred for the treatment of prognathism of the lower jaw. Laboratory data showed that partial thromboplastin time was slightly increased, so additional testing was performed and revealed low VWF. The patient was then administered 1‐desamino‐8‐D‐arginine vasopressin before orthognathic surgery and experienced no hemorrhagic episodes perioperatively.ConclusionAs both OI patients and low VWF patients are at greater risk of hemorrhage, surgery in such cases should be performed with due consideration of and preparation for bleeding.

Publisher

Wiley

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