NPM1mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information inNPM1‐mutated acute myeloid leukemia-Reference-Cited by-同舟云学术

NPM1mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information inNPM1‐mutated acute myeloid leukemia

Published:2019-03-18 Issue:6 Volume:94 Page:E158-E160
ISSN:0361-8609
Container-title:American Journal of Hematology
language:en
Short-container-title:Am J Hematol

Author:

Abbas Hussein A.¹^ORCID,Ravandi Farhad²,Loghavi Sanam³,Patel Keyur P.³,Borthakur Gautam²^ORCID,Kadia Tapan M.²^ORCID,Jabbour Elias²^ORCID,Takahashi Koichi²,Cortes Jorge²^ORCID,Issa Ghayas C.²,Konopleva Marina²,Kantarjian Hagop M.²^ORCID,Short Nicholas J.²^ORCID

Affiliation:

1. Hematology and Oncology Fellowship ProgramThe University of Texas MD Anderson Cancer Center Houston Texas

2. Department of LeukemiaThe University of Texas MD Anderson Cancer Center Houston Texas

3. Department of HematopathologyThe University of Texas MD Anderson Cancer Center Houston Texas

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.25454

Reference6 articles.

1. AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features

2. Genomic Classification and Prognosis in Acute Myeloid Leukemia

3. Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia

4. High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML

5. A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia

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