Affiliation:
1. Key Laboratory for Green Organic Synthesis and Application of Hunan Province Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education College of Chemistry Xiangtan University Xiangtan 411105 China
2. Department School of Chemistry and Chemical Engineering Henan Normal University Xinxiang 453007 China
Abstract
AbstractA regioselective synthesis of 2‐amino‐para‐iminonaphthoquinones and 4‐amino‐1,2‐naphthoquinones was described via the substrate‐dependent divergent multi‐functionalization of β‐tetralone with primary and secondary amines under metal‐free conditions. This developed strategy features extremely green and mild conditions (O2 as oxidant, ethanol as solvent under ambient temperature), broad substrate scope, and various pharmaceutical derivatizations.magnified image
Funder
National Natural Science Foundation of China