Electrosynthesis of Tetrasubstituted Sulfonated Pyrazoles through Iodide‐Mediated Multicomponent Coupling

Abstract

AbstractAn electrochemical protocol for synthesizing tetra‐substituted sulfonated pyrazoles is developed. The notable feature of this method is the electrocatalytic generation of an active iodine species, which enables the direct use of 1,3 dicarbonyls as the reactant and also eliminates the necessity for external electrolytes. A wide range of functionalities are compatible under the electrocatalytic condition, resulting good to excellent production of the desired pyrazole derivatives. Detailed synthetic and electrochemical studies enlighten the electrocatalytic pathway.