Synthesis of Benzo[e][1,3]thiazin‐4‐ones via PPh3‐Promoted Cyclization of Benzo[c][1,2]dithiol‐3‐ones and Amidines

Author:

Liu Xiaobing1,Lv Wenxin2,Dong Junjie2,Liu Zekai2,Hu Feng2,Zhou Chuncheng2,Zhou Yao2ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering Zhoukou Normal University Zhoukou Henan 466000 People's Republic of China

2. Hubei Key Laboratory of Pollutant Analysis & Reuse Technology College of Chemistry and Chemical Engineering Hubei Normal University Huangshi Hubei 435002 People's Republic of China

Abstract

AbstractA phosphine‐mediated cyclization of benzo[c][1,2]dithiol‐3‐ones and amidines is demonstrated herein. Triphenylphosphine was harnessed as the activating reagent to facilitate the ring‐opening of benzo[c][1,2]dithiol‐3‐ones via S−S bond cleavage. This PPh3‐Promoted cyclization reaction of benzo[c][1,2]dithiol‐3‐ones enabled to forge a diverse array of 1,3‐benzothiazones in decent yields with wide substrate scope under mild conditions.

Publisher

Wiley

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