Metal‐Free Photocyclization/Oxidation Cascade Constructing Quinoline‐2‐ones and Tetrahydrocarbazolones

Author:

Hao Yanke1,Huang He1ORCID

Affiliation:

1. School of Chemistry Sun Yat-Sen University Guangzhou 510275 People's Republic of China

Abstract

AbstractWe reported a one‐pot photocyclization/ oxidation cascade of N‐aryl acrylamides to afford quinoline‐2‐ones. Thioxanthone was used as a bifunctional energy transfer agent to mediate both photocyclization and generation of singlet oxygen, the latter facilitates the dehydrogenation of dihydroquinoline‐2‐one intermediate. This cascade strategy also supports the 5‐endo‐trig cyclization to synthesize tetrahydrocarbazolones from phenylamino cyclohexenones.

Funder

Sun Yat-sen University

Publisher

Wiley

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