1,6‐Addition Reactions of Difluoroenol Silyl Ethers with Benzoquinones and Quinonediimines To Access Difluorooxymethyl and Difluoroaminomethyl Compounds-Reference-Cited by-同舟云学术

1,6‐Addition Reactions of Difluoroenol Silyl Ethers with Benzoquinones and Quinonediimines To Access Difluorooxymethyl and Difluoroaminomethyl Compounds

Published:2023-11-28 Issue:24 Volume:365 Page:4550-4555
ISSN:1615-4150
Container-title:Advanced Synthesis & Catalysis
language:en
Short-container-title:Adv Synth Catal

Author:

Hong Peng¹²,Xu Jinjing¹,Li Jinshan¹,Zhu Xiaolei¹^ORCID,Ying Anguo²,Wang Zhiming¹,Yang Jianguo¹^ORCID

Affiliation:

1. Advanced Research Institute and School of Pharmaceutical Sciences Taizhou University Jiaojiang Zhejiang 318000 People's Republic of China

2. Department of Chemistry and Chemical Engineering Qufu Normal University Qufu Shandong 273100 People's Republic of China

Abstract

AbstractThe etherification and amination of difluoroenol silyl ethers with benzoquinones and quinonediimines were achieved by using hexafluoroisopropanol (HFIP) as the solvent. This 1,6‐addition reaction could construct difluorooxymethyl and difluoroaminomethyl compounds under metal‐free conditions. It is preliminarily speculated that the reaction took place through a single electron transfer (SET) process.

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adsc.202300877

Reference66 articles.

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