The Puzzling Issue of ‘Vehicle-Treated Control’ when Using Ethanol as Drug Carrier for MCF-7 Cells

Author:

Chan Robbie Yat-Kan1,Lee Kenneth Ka-Ho2,Wong Wai-Yeung3,Tang Johnny Cheuk-On4,Lam Kim-Hung4,Cheng Chor-Hing4,Lau Fung-Yi5,Kok Stanton Hon-Lung2,Gambari Roberto6,Chui Chung-Hin345

Affiliation:

1. Programme of Food Science and Technology, Division of Science and Technology; Beijing Normal University-Hong Kong Baptist University United International College; Zhuhai China

2. MOE Key Laboratory for Regenerative Medicine, School of Biomedical Sciences; The Chinese University of Hong Kong; Hong Kong China

3. Clinical Division, School of Chinese Medicine and Department of Chemistry; Hong Kong Baptist University; Hong Kong China

4. Department of Applied Biology and Chemical Technology; Hong Kong Polytechnic University; Hong Kong China

5. Department of Medicine and Therapeutics; The Chinese University of Hong Kong; Hong Kong China

6. Department of Life Sciences and Biotechnology; University of Ferrara; Ferrara Italy

Funder

This work is supported by the account code: 38-40-116 (Dr. C. H. Chui, HKBU). Professor R Gambari is supported by AIRC (IG-13575).

Publisher

Wiley

Subject

Pharmacology

Reference10 articles.

1. Optimization of an estrogen receptor-α transcriptional activation assay for testing a diverse spectrum of chemicals;Charles;J Appl Toxicol,2000

2. Analysis of the effects of different alcohols on MCF-7 human breast cancer cells;Etique;Ann NY Acad Sci,2004a

3. Ethanol stimulates proliferation, ERα and aromatase expression in MCF-7 human breast cancer cells;Etique;Int J Mol Med,2004b

4. Ethanol stimulates the secretion of matrix metalloproteinases 2 and 9 in MCF-7 human breast cancer cells;Etique;Oncol Rep,2006

5. Ethanol modulates the growth of human breast cancer cells in vitro;Izevbigie;Exp Biol Med,2002

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