Comparison of Two Highly Automated ECG Algorithms for Detection of Drug-Induced Cardiac Ion Channel Block-Reference-Cited by-同舟云学术

Comparison of Two Highly Automated ECG Algorithms for Detection of Drug-Induced Cardiac Ion Channel Block

Published:2017-12-08 Issue:2 Volume:104 Page:356-363
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Brockway Marina¹,Fossa Anthony A.²^ORCID,Mason Jay W.³⁴

Affiliation:

1. VivaQuant LLC; St Paul Minnesota USA

2. Fossa Consulting LLC; Mystic Connecticut USA

3. Spaulding Clinical Research; West Bend Wisconsin USA

4. Division of Cardiology; University of Utah; Salt Lake City Utah USA

Funder

National Institute on Drug Abuse

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.934/fullpdf

Reference17 articles.

1. ICH Guidance for Industry E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs 2005 2015 http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm073153.pdf

2. Dealing with global safety issues: was the response to QT-liability of non-cardiac drugs well coordinated?;Stockbridge;Drug Saf.,2013

3. Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine and verapamil;Johannesen;Clin. Pharmacol. Ther.,2014

4. An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel;Crumb;J. Pharmacol. Toxicol. Methods.,2016

5. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes development;Redfern;Cardiovasc. Res.,2003

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