Male pediatric, adolescent, and young adult reproductive survivorship

Author:

Burns Karen12ORCID,Phillips Christine12,Brannigan Robert3,Franklin Anna45,Howell Jonathan16ORCID,Schmidt Deb7,Sopfe Jenna45,Appiah Leslie Coker89,Anazodo Antoinette101112ORCID

Affiliation:

1. Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio

2. Division of Oncology Cincinnati Children's Hospital Medical Center Cincinnati Ohio

3. Department of Urology Northwestern University Feinberg School of Medicine Chicago Illinois

4. Center for Cancer and Blood Disorders Children's Hospital of Colorado Aurora Colorado

5. Department of Pediatrics University of Colorado School of Medicine Aurora Colorado

6. Division of Endocrinology Cincinnati Children's Hospital Medical Center Cincinnati Ohio

7. Division of Oncology Children's Hospital of Wisconsin Milwaukee Wisconsin

8. Department of Obstetrics and Gynecology University of Colorado School of Medicine Denver Colorado

9. Department of Surgery, Pediatric and Adolescent Gynecology Children's Hospital Colorado Denver Colorado

10. Kids Cancer Centre Sydney Children's Hospital Randwick New South Wales Australia

11. Nelune Comprehensive Cancer Centre Randwick New South Wales Australia

12. School of Women's and Children's University of New South Wales Sydney New South Wales Australia

Abstract

AbstractAs pediatric, adolescent, and young adult cancer survival rates increase, emphasis is placed on reducing late effects, including reproductive complications and potential impact to fertility. Male survivors are at risk of abnormalities in sperm, hormone deficiencies, and sexual dysfunction. This can impact one's progression into puberty and ability to have a biological child and impacts quality of life following treatment. Access to reproductive care is important and requires patient assessment and appropriate referral to reproductive specialists. This review addresses reproductive complications associated with therapy, standard‐of‐care testing, and therapeutic interventions. The psychologic impact on psychosexual functioning is also addressed.

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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