Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2‐methoxyestradiol

Author:

Lakhani Nehal J.,Sparreboom Alex,Xu X.i.a.,Veenstra Timothy D.,Venitz Jürgen,Dahut William L.,Figg William D.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference33 articles.

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2. Antiestrogen action of 2‐hydroxyestrone on MCF‐7 human breast cancer cells;Schneider;J Biol Chem,1984

3. Formation, metabolism, and physiologic importance of catecholestrogens;Ball;Am J Obstet Gynecol,1990

4. Free radical generation by redox cycling of estrogens;Liehr;Free Radic Biol Med,1990

5. Molecular origin of cancer: Catechol estrogen‐3,4‐quinones as endogenous tumor initiators;Cavalieri;Proc Natl Acad Sci USA,1997

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