Syndecans in chronic inflammatory and autoimmune diseases: Pathological insights and therapeutic opportunities
Author:
Affiliation:
1. Department of Pharmaceutical SciencesWashington State University College of PharmacySpokaneWashington
2. Division of RheumatologyUniversity of Washington School of MedicineSeattleWashington
Funder
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Publisher
Wiley
Subject
Cell Biology,Clinical Biochemistry,Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.26388
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1. Syndecans – key regulators of cell signaling and biological functions
2. Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice
3. High syndecan-1 expression is associated with favourable outcome in squamous cell lung carcinoma treated with radical surgery
4. Syndecan-1 and syndecan-4 are overexpressed in an estrogen receptor-negative, highly proliferative breast carcinoma subtype
5. Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
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