Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment

Author:

Park Jae-Hyun1,Seo Sang Won1,Kim Changsoo2,Kim Geon Ha1,Noh Hyun Jin1,Kim Sung Tae3,Kwak Ki-Chang4,Yoon Uicheul5,Lee Jong Min4,Lee Jong Weon1,Shin Ji Soo6,Kim Chi Hun1,Noh Young1,Cho Hanna1,Kim Hee Jin1,Yoon Cindy W.1,Oh Seung Jun7,Kim Jae Seung7,Choe Yearn Seong8,Lee Kyung-Han8,Lee Jae-Hong9,Ewers Michael10,Weiner Michael W.,Werring David J.11,Na Duk L.1

Affiliation:

1. Department of Neurology; Sungkyunkwan University School of Medicine, Samsung Medical Center; Seoul; Korea

2. Department of Preventive Medicine; Yonsei University College of Medicine; Seoul; Korea

3. Department of Radiology; Sungkyunkwan University School of Medicine, Samsung Medical Center; Seoul; Korea

4. Department of Biomedical Engineering; Hanyang University; Seoul; Korea

5. Department of Biomedical Engineering; Catholic University of Daegu; Seoul; Korea

6. Department of Nuclear Medicine; Sungkyunkwan University School of Medicine; Samsung Medical Center; Seoul; Pfizer Korea

7. Department of Nuclear Medicine; University of Ulsan College of Medicine; Asan Medical Center; Seoul; Korea

8. Department of Nuclear Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center; Seoul; Korea

9. Department of Neurology, University of Ulsan College of Medicine; Asan Medical Center; Seoul; Korea

10. Institute for Stroke and Dementia Research; Ludwig-Maximilians-University; Munich; Germany

11. Department of Brain Repair and Rehabilitation; UCL Institute of Neurology, Queen Square; London; United Kingdom

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference34 articles.

1. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds;Fazekas;Am J Neuroradiol,1999

2. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting;Cordonnier;Brain,2007

3. Small chronic hemorrhages and ischemic lesions in association with spontaneous intracerebral hematomas;Tanaka;Stroke,1999

4. Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms;Attems;Acta Neuropathol,2005

5. Cerebral Microbleeds

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