Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulation-Reference-Cited by-同舟云学术

Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulation

Published:2014-04-10 Issue:6 Volume:44 Page:1770-1780
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Shiheido Hirokazu¹,Aoyama Takane¹,Takahashi Honami¹,Hanaoka Kaori²,Abe Tomoki³,Nishida Emi⁴,Chen Chen¹,Koga Orie¹,Hikida Masaki¹,Shibagaki Yoshio⁵,Morita Akimichi⁴,Nikawa Takeshi³,Hattori Seisuke⁵,Watanabe Takeshi¹,Shimizu Jun¹

Affiliation:

1. Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine; Kyoto University; Kyoto Japan

2. Pharmacology Research Laboratories, Drug Discovery Research; Astellas Pharma Inc.; Tsukuba Japan

3. Departments of Nutritional Physiology, Institute of Health Biosciences; The University of Tokushima Graduate School; Tokushima Japan

4. Department of Geriatric and Environmental Dermatology; Nagoya City University Graduate School of Medical Sciences; Nagoya Japan

5. Division of Biochemistry, School of Pharmaceutical Sciences; Kitasato University; Tokyo Japan

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference43 articles.

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5. Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes;Cantrell;Proc. Natl. Acad Sci. USA,1985

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