High expression of integrin β 6 in association with the Rho–Rac pathway identifies a poor prognostic subgroup within HER 2 amplified breast cancers

Author:

Desai Krisha1,Nair Madhumathy G.1,Prabhu Jyothi S.1,Vinod Anupama1,Korlimarla Aruna1,Rajarajan Savitha1,Aiyappa Radhika1,Kaluve Rohini S.1,Alexander Annie1,Hari P. S.1,Mukherjee Geetashree2,Kumar Rekha V.2,Manjunath Suraj3,Correa Marjorrie3,Srinath B. S.4,Patil Shekhar4,Prasad M. S. N.4,Gopinath K. S.5,Rao Raman N.5,Violette Shelia M.6,Weinreb Paul H.6,Sridhar T. S.1

Affiliation:

1. Division of Molecular Medicine St. John's Research Institute Bangalore India

2. Kidwai Medical Institute of Oncology Bangalore India

3. St. John's Medical College and Hospital Bangalore India

4. Shankara Cancer Hospital and Research Centre Bangalore India

5. Rangadore Memorial Hospital Bangalore India

6. Biogen Inc. Cambridge MA

Funder

Nadathur Estates Pvt. Ltd

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference36 articles.

1. Characterization of the integrin alphavbeta6 as a fibronectin‐binding protein;Busk M.;J. Biol. Chem.,1992

2. Defining the Role of Integrin αvβ6 in Cancer

3. β1 and β4 integrins: from breast development to clinical practice

4. Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling;Breuss J. M.;J. Cell Sci.,1995

5. αv-Integrin isoform expression in primary human tumors and brain metastases

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