Population Pharmacokinetics of Brentuximab Vedotin in Patients With CD30-Expressing Hematologic Malignancies
Author:
Affiliation:
1. Seattle Genetics, Inc.; Bothell WA USA
Funder
Seattle Genetics
Millennium Pharmaceuticals, Inc.,
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.920/fullpdf
Reference26 articles.
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2. Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma;Younes;J Clin Oncol,2012
3. Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates;Sutherland;J Biol Chem,2006
4. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity;Francisco;Blood,2003
5. Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate;Okeley;Clin Cancer Res,2010
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