Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC‐Derived Neural Cells in a Primate Model of Parkinson's Disease-Reference-Cited by-同舟云学术

Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC‐Derived Neural Cells in a Primate Model of Parkinson's Disease

Published:2012-04-09 Issue:5 Volume:30 Page:935-945
ISSN:1066-5099
Container-title:STEM CELLS
language:en
Short-container-title:STEM CELLS

Author:

Doi Daisuke¹²³,Morizane Asuka¹²,Kikuchi Tetsuhiro¹³,Onoe Hirotaka⁴,Hayashi Takuya²⁴,Kawasaki Toshiyuki⁴,Motono Makoto²,Sasai Yoshiki⁵,Saiki Hidemoto¹,Gomi Masanori¹³,Yoshikawa Tatsuya¹,Hayashi Hideki¹³,Shinoyama Mizuya¹³,Refaat Mohamed M.¹³,Suemori Hirofumi⁶,Miyamoto Susumu³,Takahashi Jun¹²³

Affiliation:

1. Department of Biological Repair, Institute for Frontier Medical SciencesInstitute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

2. Department of Cell Growth and Differentiation, Center for iPS Cell Research and ApplicationInstitute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

3. Department of Neurosurgery, Clinical Neuroscience, Graduate School of Medicine,Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

4. Functional Probe Research Laboratory, RIKEN Center for Molecular Imaging Science, Kobe, Japan

5. Organogenesis and Neurogenesis Group, RIKEN Center for Developmental Biology, Kobe, Japan

6. Laboratory of Embryonic Stem Cell Research, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

Funder

Grant-in-Aid for Scientific Research from the JSPS

Kobe Cluster

Project for Realization of Regenerative Medicine from the MEXT

Health and Labor Sciences Research Grant for Research on Regenerative Medicine for Clinical Application

Society of Catecholamine and Nervous Disease

Michael J. Fox Foundation for Parkinson's Research

Publisher

Oxford University Press (OUP)