A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury

Author:

Niu Yong‐Min1ORCID,Qin Hao‐Yue2ORCID,Liu Jin‐Xiang1ORCID,Li Xin‐Yi2,Wang An‐Su3,Sun Ling‐Xia3,Huang Ni‐Jiao3,Yang Chang‐Wei3,Cao Yu3,Bai Tao1,Lan Yang1,Liu Sheng4,Yuan Hao13ORCID

Affiliation:

1. Department of Basic Medical Sciences, College of Basic Medical Sciences Kunming Medical University Kunming Yunnan China

2. Department of Anesthesiology Southwest Medical University Luzhou Sichuan China

3. Department of Orthopedics Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China

4. Department of Pharmacology, Pharmacology Institute Heidelberg University Heidelberg Germany

Abstract

AbstractDecubitus ulcers are a common spinal cord injury (SCI) complication that puts patients' lives in danger and has emerged as a more prevalent issue in modern clinical rehabilitation and care. Decubitus ulcers in humans can currently be treated in a number of different ways, but there are fewer studies on how to treat and care for decubitus ulcers in macaques. To treat a 20‐year‐old adult male macaque monkey with SCI and decubitus ulcers after a quarter transection of the thoracic spinal cord, a number of scientific care procedures and pharmaceutical treatments, such as dietary changes and topical or intravenous administration of medication, were carried out and continuously monitored in real‐time. In comparison to the untreated group, we observed a significant improvement in decubitus wound healing in the macaques. In this article, we provide a good protocol for decubitus ulcer care after SCI and suggest that future experimental animal modeling needs to focus on issues such as care for postoperative complications.

Publisher

Wiley

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