IRF4 L116R mutation promotes proliferation of chronic lymphocytic leukemia B cells inducing MYC-Reference-Cited by-同舟云学术

IRF4 L116R mutation promotes proliferation of chronic lymphocytic leukemia B cells inducing MYC

Published:2021-08-25 Issue:5 Volume:39 Page:707-711
ISSN:0278-0232
Container-title:Hematological Oncology
language:en
Short-container-title:Hematological Oncology

Author:

Benatti Stefania¹,Atene Claudio Giacinto¹,Fiorcari Stefania¹,Mesini Nicolò¹,Martinelli Silvia¹,Zucchini Patrizia¹,Bacchelli Francesca¹,Maccaferri Monica²,Debbia Giulia¹,Potenza Leonardo¹,Rossi Davide³^ORCID,Vallisa Daniele⁴,Trentin Livio⁵,Gaidano Gianluca⁶,Luppi Mario¹,Marasca Roberto¹,Maffei Rossana²^ORCID

Affiliation:

1. Division of Hematology Department of Medical and Surgical Sciences University of Modena and Reggio Emilia Modena Italy

2. Department of Oncology and Hematology Hematology Division Azienda Ospedaliero‐Universitaria of Modena‐Policlinico Modena Italy

3. Hematology Oncology Institute of Southern Switzerland and Institute of Oncology Research Bellinzona Switzerland

4. Division of Hematology Guglielmo da Saliceto Hospital Piacenza Italy

5. Hematology and Clinical Immunology Department of Medicine University of Padua Padua Italy

6. Division of Hematology Department of Translational Medicine University of Eastern Piedmont Novara Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Cancer Research,Oncology,Hematology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hon.2915

Reference23 articles.

1. Interferon regulatory factor 4 and 8 in B-cell development

2. Graded Expression of Interferon Regulatory Factor-4 Coordinates Isotype Switching with Plasma Cell Differentiation

3. The diverse roles of IRF4 in late germinal center B-cell differentiation

4. IRF-4 functions as a tumor suppressor in early B-cell development

5. A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

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2. Role of Notch2 pathway in mature B cell malignancies;Frontiers in Oncology;2023-01-04

3. The dynamic functions of IRF4 in B cell malignancies;Clinical and Experimental Medicine;2022-12-10

4. Point mutation L116R in interferon‐regulatory factor 4 differentially impacts key cytokine production in Th2, Th9, and Th17 cells;European Journal of Immunology;2022-09-19

5. Detection of early seeding of Richter transformation in chronic lymphocytic leukemia;Nature Medicine;2022-08