Antineoplastic Isoflavonoids Derived from Intermediateortho-Quinone Methides Generated from Mannich Bases

Author:

Frasinyuk Mykhaylo S.123,Mrug Galyna P.3,Bondarenko Svitlana P.4,Khilya Volodymyr P.4,Sviripa Vitaliy M.12,Syrotchuk Oleksandr A.5,Zhang Wen16,Cai Xianfeng16,Fiandalo Michael V.7,Mohler James L.7,Liu Chunming16,Watt David S.126

Affiliation:

1. Department of Molecular and Cellular Biochemistry; College of Medicine; University of Kentucky; Lexington KY 40536-0596 USA

2. Center for Pharmaceutical Research and Innovation; College of Pharmacy; University of Kentucky; Lexington KY 40536-0509 USA

3. Department of Chemistry of Bioactive Nitrogen-Containing Heterocyclic Bases; Institute of Bioorganic Chemistry and Petrochemistry; National Academy of Science of Ukraine; Kyiv 02094 Ukraine

4. Department of Chemistry; Taras Shevchenko Kyiv National University; Kyiv 01601 Ukraine

5. Central Laboratory for Quality Control of Medicines and Medical Products; Kyiv 04053 Ukraine

6. Lucille Parker Markey Cancer Center; University of Kentucky; Lexington KY 40536-0093 USA

7. Department of Urology; Roswell Park Cancer Institute; Buffalo NY 14263 USA

Funder

National Institutes of Health (NIH)

Office of the Dean of the College of Medicine (University of Kentucky)

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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