Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies-Reference-Cited by-同舟云学术

Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies

Published:2018-11-06 Issue:21 Volume:13 Page:2271-2280
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Möller Carsten¹,Bone Wilhelm²,Cleve Arwed²,Klar Ulrich³,Rotgeri Andrea²,Rottmann Antje²,Schultze‐Mosgau Marcus‐Hillert²,Wagenfeld Andrea²,Schwede Wolfgang²^ORCID

Affiliation:

1. Bayer AGMarket Access 13342 Berlin Germany

2. Bayer AGPharmaceuticals R&D 13342 Berlin Germany

3. Retired, formerly at: Bayer AGPharmaceuticals R&D 13342 Berlin Germany

Funder

Bayer

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201800487

Reference48 articles.

1. Investigational developments for the treatment of progesterone-dependent diseases

2. Regio and stereospecific synthesis of 11β-substituted 19-norsteroids

4. Distinct Temporal and Spatial Activities of RU486 on Progesterone Receptor Function in Reproductive Organs of Ovariectomized Mice

5. Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficacy and safety of vilaprisan in women with uterine fibroids: data from the ASTEROID 3 randomized controlled trial;F&S Science;2023-11

2. Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding: the UCON randomised controlled trial and mechanism of action study;Efficacy and Mechanism Evaluation;2023-10

3. Research advances in drug therapy of endometriosis;Frontiers in Pharmacology;2023-06-21

4. Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trial;eClinicalMedicine;2023-06

5. StackPR is a new computational approach for large-scale identification of progesterone receptor antagonists using the stacking strategy;Scientific Reports;2022-09-30